ZFIN Image: Bandla et al., 2022, Figure 7

Image

Figure Caption

Figure 7 ret and sox10 mutants lack GFP⁺ ENS cells. (A–A”) In 6 dpf wildtype siblings (wt sibs), GFP⁺ cells colocalize with the pan-neuronal markers Elavl and acetylated Tubulin (AT, white arrows) in ENS neurons; Elavl⁻/AT⁻/GFP⁺ cells with a characteristic teardrop shape are enteroendocrine cells (green arrow). In 6 dpf ret (B–B”) or sox10 (C–C”) homozygous mutants, GFP⁺ ENS neurons are absent. AT⁺ processes are the vagal innervation to the gut (magenta arrows). Elavl⁻/AT⁻/GFP⁺ enteroendocrine cells are still present (green arrows). We analyzed ≥30 larvae per genotype. (A–C), maximum projections of dissected guts. Scale bar = 100 µm.

Figure Data

Phenotype details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Mol. Sci.