ZFIN Image: Terai et al., 2021, Fig. 4

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Fig. 4

Figure 4.An N-methyl-d-aspartate (NMDA) receptor antagonist attenuated spreading depolarization (SD) propagation in the zebrafish tectum. A: a schematic of the experimental process used to assess the effect of MK-801 (NMDA receptor antagonist) on SD in the zebrafish tectum. Representative traces of direct current (DC) potentials at the proximal (Rec1, solid lines) and distal (Rec2, dashed lines) electrodes in the optic tectum of the zebrafish pretreated with vehicle (B) and MK-801 (C). Bar graphs with dot-whisker plots of SD velocity (D), amplitude (E), and duration (F) observed in zebrafish pretreated with vehicle (n = 8) and MK-801 (n = 4). *P < 0.05. NS, not significant.

Acknowledgments

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