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Fig. 2

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ZDB-IMAGE-220904-11
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Figures for Cao et al., 2022
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Figure Caption

Fig. 2 The antibacterial effects of zebrafish CD44a and NOD1 are independent of each other.

a The quantification analysis of mRNA levels of key genes involved in the NOD1-RIPK2 signaling pathway in the WT, CD44a−/−-14del and CD44a−/−-10IS zebrafish larvae, as determined by qRT-PCR. Quantification data represent the expression level of genes compared with those in the WT zebrafish. b Zebrafish larvae from the WT and NOD1−/− mutants microinjected with p3×FLAG or CD44a_tv1-FLAG were collected at the indicated post-infection time points, and homogenates were made for CFU counts. c Zebrafish larvae from the WT and NOD1−/− mutants microinjected with p3×FLAG or CD44a_tv2-FLAG were collected at the indicated post-infection time points, and homogenates were made for CFU counts. d Zebrafish larvae from the WT and CD44a−/−-14del mutants microinjected with p3×FLAG or NOD1-FLAG were collected at the indicated post-infection time points, and homogenates were made for CFU counts. For ad, the data are presented as means ± SD (n = 3). *p < 0.05, **p < 0.01; ns not significant.

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