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Fig. 2 Extracted chromatograms of metabolites. (a) nucleotides: cytidine, adenosine, and 2-deoxyguanosine; (b) amines: serotonin, thiamine, and tyramine; (c) amino acids: glutamate, lysine, and tyrosine; (d) others: tryptophan, carnitine, and pantothenic acid; obtained on the HILIC column with solvent additives: 10 mM NH4HCO2 (pH = 3) (left); 5 mM NH4HCO2 (pH = 3) (middle); 10 mM NH4Ac (pH = 6.5) (right) in positive ionization mode.
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