ZFIN Image: Scaramella et al., 2022, Figure 3.

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Figure 3.

Extended exposure to DMSO does not increase mortality, delays in hatching, or abnormal sensorimotor responses. A, Exposure of zebrafish larvae to DMSO (0.05%) from 0 to 5 dpf did not change the mortality rate (DMSO group = 22.00 ± 5.92%, n = 50) compared with a control group exposed only to E3 (E3 group = 18.75 ± 4.39%, n = 80) according to an unpaired t test (t₍₁₂₈₎ = 0.45, p = 0.66). B, Extended exposure (5 d) to DMSO (0.05%) did not significantly delay hatching in zebrafish compared with fish exposed to E3 solution (DMSO group = 2.50 ± 2.50%, n = 40; E3 group = 7.58 ± 3.28%, n = 66; unpaired t test; t₍₁₀₄₎ = 1.09, p = 0.28). C, An unpaired t test (t₍₁₀₄₎ = 1.45, p = 0.15) revealed no significant differences in startle response probability between the DMSO group (88.33 ± 3.00%, n = 40) and the E3 group (93.18 ± 1.87%, n = 66).

Acknowledgments

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