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Figure 4—figure supplement 1.

ID: ZDB-IMAGE-220416-98
Source: Figures for Yang et al., 2022

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Figure Caption

Figure 4—figure supplement 1. Targeted ablation of peri-islet neurons affects islet nerve density and islet cell activity.

(A) 100 hpf Et(1121A:GAL4FF); Tg(UAS:GCaMP6s) zebrafish immuno-stained for acetylated Tubulin (nerves) and counterstained with DAPI (DNA). (B) Islet nerve density is quantified following ablation of peri-islet neurons; mean ± standard error of the mean (SEM), n = 7 animals, p value from t-test. (C) Average homotypic (delta–delta and alpha–alpha) and heterotypic (delta–beta and alpha–delta) cell correlation coefficients with cell distance distribution from 1 (close) to 10 (far), mean ± SEM and linear regression (solid lines) with 95% confidence intervals; n = 11–12 animals, p values of slope and intercept from simple linear regression.

Acknowledgments

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