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FIGURE 2
Haplotypes of the families and their derivation from the original risk haplotype, as shown by the compressed haplotype blocks labeled by the first SNP from the c.75C > A mutation (here shown in the figure as NC_000001.11:g. 108950376G > T for consistency with other SNPs). The original risk haplotype is shown in dark blue, and recombined haplotype blocks are shown in light blue. The mutation is shown in red and haplotypes in families 61328 and 61244 with the identical initial allele but part of a haplotype differing from those families 61224 (the founder haplotype) and 61030/61334 respectively are shown in gold.