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Figure 2
Zoo protein alignments of AQP0 extracellular loops. Amino acid alignment of extracellular loops A, C, and E of AQP0 across selected mammalian and piscine species. RasMol coloring. Human (Homo sapiens), bovine (Bos taurus), mouse (Mus musculus), and rat (Rattus norvegicus) AQP0 (also known as MIP) are shown. The fish Aqp0s shown include MIPfun of killifish (Fundulus heteroclitus) and duplicated Aqp0s for zebrafish (Danio rerio) and Atlantic salmon (Salmo salar). Two amino acids of interest indicated as boxed sites 110 and 195 were mutated in this study.
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