ZFIN Image: Travnickova et al., 2020, Figure 1

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Figure 1

Zebrafish tools to deconvolve melanoma cell states. Zebrafish represents a powerful model to tackle melanoma heterogeneity and plasticity. A parallel study of developmental lineages (left) and melanoma initiation and residual disease modeling (right) allows simultaneously screening and detailed single-cell and functional analysis of melanoma within a complex microenvironment. Examples of the individual technologies to evaluate the varied aspects of melanoma cell states, plasticity, and microenvironmental factors are presented.

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Invest. Dermatol.