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Figure Caption
Figure 4 Molecular docking of arecoline with endogenous zebrafish muscarinic acetylcholine receptor (mAChR). (A) The identified binding pocket in the middle of the hollow cylinder of the eight sub-types homology modeling structures of mAChR (M3a as an example). Two-dimensional (2D) (B) and 3D (C) illustrations of interactions between arecoline and endogenous zebrafish mAChR M3a showing the hydrogen bond formation between arecoline and mAChR M3a at position Tyr536 (highlighted by the green dotted line).
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