ZFIN Image: Duong et al., 2021, Fig. 9

Image

Figure Caption

Fig. 9 Anterior pharyngeal muscles are unaffected in RA-deficient embryos. (A-B″) IHC for ZsYellow+ (green) and Mhc+ (red) pharyngeal muscles in DMSO- and DEAB-treated nkx2.5:ZsYellow embryos at 72 hpf. Views are frontal with anterior left and dorsal up. Brackets indicate the dorsal pharyngeal muscles. Dorsal mandibular arch: lap - levator arcus palatini, do - dilatator opercula. Dorsal hyoid arch: ah - adductor hyomandibulae, ao - adductor opercula. The dashed lines indicate the nkx2.5:ZsYellow+ muscles. The dorsal mandibular and hyoid arch muscles are dysmorphic in RA-deficient embryos. Number of embryos examined: DMSO-treated n = 9, DEAB-treated n = 6. Scale bar – 33 μm.

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Reprinted from Developmental Biology, 473, Duong, T.B., Holowiecki, A., Waxman, J.S., Retinoic acid signaling restricts the size of the first heart field within the anterior lateral plate mesoderm, 119-129, Copyright (2021) with permission from Elsevier. Full text @ Dev. Biol.