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Fig. 5 Unlike transplanted caudal-SrRCs, transplantation of rostral-SrRCs could significantly improve neuronal regeneration of SCI-adult zebrafish. (a) Schematic diagram illustrating the effect of SrRCs transplantation on neuronal regeneration of SCI-adult fish. SCI was performed on huORFZ embryos at 72 hpf (hours-post-fertilization). (b–g) The locomotive route of each fish was tracked in line, and its swimming distance (cm) was calculated. The results obtained from non-treated WT (WT; positive control), SCI-treated zebrafish (SCI-only; negative control) and GFAP-cell transplantation (sham control) were compared to (b,c) SrRCs transplantation, (d,e) rostral-SrRCs transplantation and (f,g) caudal-SrRCs transplantation. Two-way ANOVA with Bonferroni multiple comparisons test (***p < 0.01, **p < 0.1; n = 10). Error bars indicate s.e.m. dpt: days post-transplantation; ns: not significant.