ZFIN Image: Turan et al., 2020, Fig. 7

Image

Figure Caption

Fig. 7 Figure 7. Computer simulations of rabbit ventricular myocytes. Cardiomyocytes were paced at 2.5 Hz under three different conditions: transduced with adenovirus encoding GFP with intracellular sodium concentration [Na⁺]i unclamped (red traces); adenovirally transduced causing LITAF overexpression with [Na⁺]i unclamped (blue traces); and adenoviral overexpression of LITAF with [Na⁺]i clamped to the same average steady-state 11 mm value reached under GFP (green traces). Transmembrane voltage V (A), cytosolic calcium concentration [Ca2⁺]iB), [Na⁺]i C), L-type calcium current ICa,L (D), Na⁺/Ca²⁺ exchanger current INCX (E), Na⁺/K⁺-pump current INaK (F), slowly activating delayed rectifier K⁺ current IKs (G), rapidly activating delayed rectifier K⁺ current IKr (H), fast sodium current INa (I), and late sodium current INaL (J).

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J. Biol. Chem.