ZFIN Image: Knüfer et al., 2020, Figure 4

Image

Figure Caption

Figure 4 <italic>cdh2ΔEC</italic> expression results in mispositioning of zebrafish trochlear neurons along the dorsoventral axis.

(A–B) Lateral view maximum intensity projections of nIII and nIV of wild-type Isl1:GFP and cdh2ΔEC larvae at 72 hpf. Dotted lines represent the midbrain-hindbrain boundary. OMN, oculomotor nerve; TN, trochlear nerve. (C) Measurements of dorsoventral extent of nIV at 72 hpf. Dots represent individual larvae. Error bars represent median and range. n = 14 larvae from two clutches for each genotype, **p=0.0042, two-tailed Mann-Whitney U. Larvae were mounted laterally to align both eyes prior to imaging. Where necessary, images were resampled to align bilateral ocular motor nuclei to the same plane and oriented so that the edge of the neuropil was directly parallel to the anterior-posterior axis.

Figure 4—source data 1.

Acknowledgments

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