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Figure 7.

ID: ZDB-IMAGE-200421-65
Source: Figures for Scaletti et al., 2020

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Figure Caption

Figure 7.

Schematic representation of the recognition of nucleotides by hMTH1. Hydrogen bond interactions of (A) N6-methyl-dAMP (N6-metA), (B) 2-oxo-dATP (2-oxoA) (23), (C) O6-methyl-dGMP (O6-metG) (10), and (D) 8-oxo-dGMP (8-oxoG) (24). Hydrogen bonds are shown as dashed lines and bond distances are given in Angstroms (Å). Deprotonated aspartates, which act as hydrogen bond acceptors, are indicated by the minus sign, where this is unambiguous.

Acknowledgments

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