ZFIN Image: Kim et al., 2020, Figure 5

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Figure Caption

Figure 5

(A) Representative echocardiograms from rats with sham MI (designated as ‘Normal’), MI and 7 d vehicle treatment (designated as ‘MI’) or MI and 7 d treatment with CPP531 (designated as ‘CPP531’). (B) Effect of CPP531 treatment on cardiac function related parameters. IVSTD: interventricular septal end diastole, LVIDd: left ventricular internal dimension, diastole, LVIDs: left ventricular internal dimension, systole, EF: ejection fraction, FS: fractional shortening and ESV: end systolic volume. n = 8 rats per treatment group; *p < 0.05 for significant improvement compared to vehicle treated rats with MI. (D) Masson’s trichrome staining of representative rat hearts. Red staining indicates cardiomyocytes and blue staining indicates fibrotic scar tissue. Scale bar = 1 mm. (E) Effect of CPP531 treatment on left ventricular wall thickness. *p < 0.05 for significantly greater ventricular wall thickness compared to vehicle treated rats with MI.

Acknowledgments

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