ZFIN Image: Costa et al., 2020, Figure 4

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Figure Caption

Figure 4

(A) Experimental setup for generating zebrafish xenografts. Cells derived from in vitro culture or primary human cells are labelled and microinjected in the PVS of 2dpf larvae. One day after injection, larvae are screened for successful injection and distributed in groups for testing chemo-, radio- and/or biological therapies. Three days after treatment, larvae (B) are fixed and processed for immunofluorescence for analysis of proliferation (C), cell death (D), angiogenesis (E), and metastatic potential (F,G). dpi: days post injection.

Acknowledgments

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