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Fig. 1 Dominant enhancer of longfin causes increased fin proportion through enhanced relative growth of the fin during development. A, B, C) Phenotype of schleier mutant zebrafish affects fin and barbel proportion and pigmentation of the adult zebrafish in a dose dependent manner. D, E, F) Segment length of lepidotrichia from adult caudal fins of wild-type, heterozygous, and homozygous schleier fish. Bar represents 200 μM. G, H, I) Close up of pigment pattern on flank of wild-type, heterozygous, and homozygous schleier fish. J) Growth curves of caudal fin length in wild-type and schleier heterozygous fish as a function of standard length (STL). Inset, Log-log plot of caudal fin length vs. STL to illustrate allometric scaling of growth. Wild-type: y = 0.9209x - 0.2495, R2 = 0.97. Schleier, y = 1.3498x - 1.7933, R2 = 0.89.
Reprinted from Developmental Biology, 456(2), Lanni, J.S., Peal, D., Ekstrom, L., Chen, H., Stanclift, C., Bowen, M.E., Mercado, A., Gamba, G., Kahle, K.T., Harris, M.P., Integrated K+ channel and K+Cl- cotransporter function are required for the coordination of size and proportion during development, 164-178, Copyright (2019) with permission from Elsevier. Full text @ Dev. Biol.