Image
|
Figure Caption
Figure 11.
Wnt5b integrates with Fak1a to mediate cell movements during gastrulation. Gastrulation cell migration is controlled by the Wnt5b pathway to activate calcium and Dsh/Daam1. Herein, we identified that Wnt5b can also integrate with FAK signalling, and both Wnt5b and Fak1a then activate small GTPase Rac1 and Cdc42 to mediate actin dynamics during gastrulation. Convergent is mainly mediated by Fak1a-mediated cell migration and extension is exerted by cell intercalation, which requires both Fak1a and Wnt5b.
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Full text @ Open Biol.