ZFIN Image: Wang et al., 2020, Figure 2

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Figure Caption

Figure 2

CYM-5478 prevents cisplatin-mediated ABR abnormalities. (A) Rats were treated with cisplatin for 3 weeks, with or without co-administration of CYM-5478, before hearing acuity was evaluated by ABR. Although all groups demonstrated similar response thresholds of ~35 dB, the cisplatin-only group exhibited increased waveform latency at all click intensities (arrow). Stimulus onset is at ~7 ms for all groups, including the time taken for sound to reach the ear. (B) Quantification of waveform V latency of 90 dB stimuli shown in (A). (n = 3–4, * p < 0.05, ** p < 0.01, ns = not significant.).

Acknowledgments

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