ZFIN Image: Jacobs et al., 2019, Figure 7.

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Figure Caption

Figure 7. Notch signalling regulates Hh response independent of primary cilia.

(A) Schematic representation of the manipulation to the Hh pathway caused by the loss of primary cilia in iguana mutants. The point of manipulation is highlighted in green with an asterisk. (B) Experimental design in C. (C) iguana mutant and sibling control embryos were incubated in either DMSO or LY-411575 at 20 hpf until fixation at 30 hpf. Whole mount in situ hybridisation was performed for ptc2 and olig2. Brackets in lateral views and dotted lines in transverse views denote the extent of the spinal cord. Arrows indicate ptc2 expression in somites. The n number for each staining is shown. Scale bars: 20 μm.

Acknowledgments

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