ZFIN Image: Jacobs et al., 2019, Figure 4.

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Figure Caption

Figure 4. Ectopic Notch activation results in increased and expanded Hh response.

hsp:rSmoM2-tRFP embryos and wild-type controls (A), or hsp:Gal4; UAS:NICD embryos and wild-type controls (B) were heat shocked at 11 hpf and stained for the expression of ptc2 and her12 at 24 hpf. Brackets in lateral views and dotted lines in transverse views denote the extent of the spinal cord. Arrows indicate ptc2 expression in somites. Note that expression of hsp:rSmoM2-tRFP resulted in an expansion of her12 expression in the vasculature compared to control embryos (arrowheads in A). The n number for each staining is shown. Scale bars: 20 μm.

Acknowledgments

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