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Fig. 3
20 week casper;mcr:NRAS melanomas engraft upon transplantation. (A) Images of tumors in recipient fish at 14 and 21 days post-transplant. (B) 20 week casper;mcr:NRAS melanomas engraft significantly better upon transplantation than 4 week donors. *p = 0.0141 calculated by a two-way ANOVA. n = 3 and 11 for 20- and 4-week old donors respectively.
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Reprinted from Developmental Biology, 449(2), McConnell, A.M., Mito, J.K., Ablain, J., Dang, M., Formichella, L., Fisher, D.E., Zon, L.I., Neural crest state activation in NRAS driven melanoma, but not in NRAS-driven melanocyte expansion, 107-114, Copyright (2018) with permission from Elsevier. Full text @ Dev. Biol.