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Fig. 10
PDMS microfluidic device for analyzing angiogenesis. Fluid flow can be controlled connecting syringe pumps to the ports, or by imposing hydrostatic gradients. Flow can be directed through the endothelial lumens (green), or across the endothelial junctions, through the central matrix gel. Sprouting occurs through the apertures that flank the central 3D matrix and is easily visualized and quantified (Adapted from [
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