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Fig. 6
The pax3a:EGFP+ populations of MMPs migrating out from the somites are reduced in met-/- mutants.
Lateral view of transgenic pax3a:EGFP expression in (A) met+/+ siblings and (B) met-/-mutant embryos at 28 hpf (n = 6 for met+/+ and n = 9 for met-/-), 36 hpf (n = 7 for met+/+and n = 5 for met-/-) and 48 hpf (n = 5 for met+/+ and n = 5 for met-/-). (C) met+/+ siblings (n = 5) and met-/- mutant (n = 5) pax3a:EGFP (green) embryos treated with BrdU (red) from 24 to 48 hpf to visualize proliferating cells. Dashed line in A indicate yolk-somite border. Abbreviations: sh: sternohyoideus; fb: fin bud; phm: posterior hypaxial muscle. Scale bar: 50 μm.
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