ZFIN Image: Eckert et al., 2019, Figure 1.

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Figure Caption

Figure 1.

Transformation of the optic vesicle into the optic cup. (a) Timeline of experimental procedure (for b–f) and orientation of the eye. (b–f) Distal flow and fissure generation. (b) Photo-converted domains (magenta) in the lens-averted layer move over the distal rims into the lens-facing domain (c–f). During this process, the fissure is induced (dotted arrow). (g–i) The optic fissure is generated from distal to proximal. (i–k) The optic stalk (arrowhead) is connected to the nasal lens-averted domain of the optic vesicle, imaging starts (g–j) at 19 hpf; scale bar, 25 µm.

Acknowledgments

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