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Fig. 1
(A–D) The csr, nco, and vns mutant phenotypes fail to form otoliths within the inner ear. However, semicircular canalformation appears to be normal. (A′–D′) All mutants fail to inflate their swim bladders, which is lethal. Imaged at 5 days post fertilization (dpf). Magnification 6.3×. (*) indicates swim bladder.
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Reprinted from Mechanisms of Development, 157, Thiessen, K.D., Grzegorski, S.J., Chin, Y., Higuchi, L., Wilkinson, C.J., Shavit, J.A., Kramer, K.L., Zebrafish otolith biomineralization requires polyketide synthase, 1-9, Copyright (2019) with permission from Elsevier. Full text @ Mech. Dev.