ZFIN Image: Weijts et al., 2018, Fig. 2

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Figure Caption

Fig. 2 Displacement of arterial ECs by venous ECs in venous ISVs. Lateral images of zebrafish embryos with anterior side facing left. Orange arrows indicate the direction of blood flow through the ISVs. Scale bars are 25 μm. a–c Representative images from four independent experiments. Venous ECs are labelled with lifeactCherry and arterial ECs are labelled with lifeactGFP and lifeactCherry. a Stills from Supplementary Movie 2. Red arrows point at an arterial EC migrating in a venous ISV, ventral part. b Stills from Supplementary Movie 2. Red arrows point at an arterial EC migrating in a venous ISV, dorsal part. c Stills from Supplementary Movie 4. Red arrows point at an arterial EC in an arterial ISV, ventral part. d–f Representative images from three independent experiments. All ECs express the photo-convertible (green-to-red) fluorescent protein DENDRA2. Red brackets highlight ECs with photo-converted DENDRA2. The photo-conversion was done at 30 hpf in the posterior cardinal vein (PCV) (d), a venous ISV (e) or an arterial ISV (f)

Acknowledgments

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