IMAGE

Fig. 2

ID
ZDB-IMAGE-181101-7
Genes
Source
Figures for Fernandez et al., 2018
Image
Figure Caption

Fig. 2

RES complex is required during zebrafish brain development.

(A) Acridine orange (ao) staining of zebrafish mutant embryos for bud13 (30–32 hpf), rbmx2 and snip1 (48 hpf). Mutants show a marked degree of cells with nuclear uptake of ao compared to WT sibling most predominantly in the head. WT: represent phenotypically wild type sibling from the same mutant fish line. (B) Maximum intensity projections of individual and merged channels (GFP and dsRed) of 3D confocal images of bud13Δ7/Δ7 and their wild-type siblings (scale bar 20 μm) in transgenic lines that label GABAergic neurons and precursors (Tg[dlx6a-1.4kbdlx5a/ dlx6a:GFP]) and glutamatergic neurons (Tg[vglut:DsRed]). WT: represent phenotypically wild type sibling from the same mutant fish line. (C) Total number of dlx5a/6a:GFP+ cells (GABAergic neurons and precursors) and vglut:DsRed+ cells (glutamatergic neurons) in the forebrain of the bud13Δ7/Δ7 (n = 3) and WT sibling (n = 4) were quantified. *** vglut: P = 2 x 10−4; ***dlx5a/6a: P = 3 x 10−4 (one-way ANOVA).

Figure Data
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS Genet.