ZFIN Image: Guzzolino et al., 2018, Fig. S1

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Figure Caption

Fig. S1

s1pr1 downregulation has a small impact on heart development. (A) Analysis of 72hpf Tg(Myl7:EGFP) embryos injected with MO-s1pr1 or MO-Ct at the reported doses (ng). The percentage of embryos with the indicated heart defects was averaged across multiple independent experiments carried out in double blind. The total number of analyzed embryos were as follows: MO-Ct (0,2ng) n=152, MO-s1pr1 (0.2ng) n=146, MO-Ct (1ng) n=101, MOs1pr1 (1 ng) n=117. T-test p= 0,014. (B) images are representative of hearts showing an enlarged atrium as a consequence of 1 ng MO-s1pr1 injection. Spotted lines highlight the atrium shape. V= ventricle A= atrium .Red scale bar = 100μm.

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Acknowledgments

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