Fig. 7
Effect of R-568 on 10 μM neomycin-induced hair cell death. 4-dpf larvae were incubated in 10 μM neomycin media with various levels of R-568 (E,J) for 1 h. After incubation, neuromast hair cells were labeled with rhodamine 123 (A–E) or FM1-43 (F–J). The addition of 16 μM R-568 partial neutralize the neuromast hair cell death induced by 10 μM neomycin (J). Data are presented as mean ± SE. A significant difference was found between values with superscript letters (a,b,c; by one-way ANOVA and Tukey’s comparison, p < 0.05). Numbers in parentheses are the numbers of neuromasts. One L1 neuromast per larva was examined.