ZFIN Image: Viader-Llargués et al., 2018, Fig. 2

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Figure Caption

Fig. 2

Zebrafish larvæ do not regenerate completely-ablated neuromasts.

(A–E) Confocal images of a 7 day follow-up of the complete ablation of a neuromast in the double transgenic line Tg[Cldnb:lynGFP; Alpl:mCherry]. (A) The site of damage was identified over subsequent days by the position of an intact reference neuromast (white asterisk). (B) Laser-mediated cell ablation produced a wound 4 hours-post-injury (hpi). (C–E) This wound was replaced by a thread of mCherry(+) cells (white arrow) 1 day-post-injury (dpi), which did not change over the subsequent 6 days. (F–J) Confocal images over a 7 day time course after the ablation of a neuromast in the double transgenic line Tg[Sox2:GFP; Alpl:mCherry]. Identically to A-E, the complete ablation of the target neuromast results in a thin trail of interneuromast cells (white arrowheads) covering the damaged area (K–N). Scale bars: 10 µm.

Acknowledgments

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