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Fig. 4
Loss of Smyd1a does not trigger the misfolded myosin response. (A) ISH analysis of smyd1a expression in unc45b mutant embryos (steif) or embryos injected with a Cas9-protein/hsp90aa1-gRNA complex, respectively. (B) mRNA levels of the muscle chaperones unc45b and hsp90aa1 are strongly upregulated in muscle cells of fla mutants, whereas their expression is not affected by loss of smyd1a. (C) Rescue of fla mutants by injection of either smyd1a- or smyd1b-mRNA.
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Full text @ Biochem. Biophys. Res. Commun.