ZFIN Image: Li et al., 2017, Fig. 4

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Figure Caption

Fig. 4

Pontin is essential for cilia motility. (A,B) Kymographs showing the rhythmic beating of motile cilia bundles in the pronephric tubule region (A) and olfactory placode (B) in wild-type zebrafish embryos at 3 dpf. pontin^{hi1055B/hi1055B} mutants (MUT) lack cilia motility. 10 wild-type and 9 pontin^{hi1055B/hi1055B} mutant embryos were observed. (C) Transmission electron micrographs of transverse sections of cilia in the pronephric tubule in wild type and pontin^{hi1055B/hi1055B} mutants at 5 dpf. Black arrowhead, outer dynein arm (ODA); red arrowhead, inner dynein arm (IDA). (D) Reduced number of ODAs, IDAs and total dynein arms per cilium section in pontin^{hi1055B/hi1055B} mutants in comparison with wild-type siblings. n=25. **P<0.01.

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Phenotype details

Acknowledgments

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