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Fig. 5
Folate targeted compounds are selectively taken up and maintained in the embryo. Brightfield and fluorescence representative images of wild-type fish exposed to either BSA conjugated to rhodamine dye or folate conjugated to BSA and rhodamine dye. After 24 h exposure to BSA based compounds, embryos were washed and transferred to standard embryo media. Exposed embryos were then imaged at 24 and 48 h after being transferred to standard embryo media and shown above.
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Reprinted from Gene expression patterns : GEP, 25-26, Jones, R.N., Erhard, S.A., Malham, M.R., Gen, A.Y., Sullivan, K., Olsen, K.W., Dale, R.M., Expression and characterization of the zebrafish orthologue of the human FOLR1 gene during embryogenesis, 159-166, Copyright (2017) with permission from Elsevier. Full text @ Gene Expr. Patterns