Image
|
Figure Caption
Fig. S3
clpb-morpholino induced microcephaly leads to a reduced brain volume in zebrafish embryo.
(A) 48 hpf embryos injected with a clpb morpholino exhibit a microcephaly phenotype (e.g reduced head size, black arrow head) as described by Capo-Chichi et al.39 (B) elavl3:GFP embryos were injected with clpb morpholino and imaged at 48 hpf under a confocal microscope. (C) The 3D-brain volume calculation shows a reduced brain volume compared to uninjected embryos.
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Full text @ Sci. Rep.