|ZFIN ID: ZDB-IMAGE-171114-7|
Syn4 is required for the migration of neural crest.
(A, B): Knockdown efficiency of syn4 MO at 9 hpf. (A): Zebrafish embryos were injected with 30 pg of pEGFP-N1-syn4 recombinant plasmid containing the MO-binding site. (B): Green fluorescence was totally abolished by co-injection with 6 ng syn4 MO. (C-D''): WISH assays of crestin (C-C''), sox10 (D-D'') at 18 somites stage. Arrows indicate the expression of crestin/sox10 in the morphants are inhibited. (E, F): Quantification of phenotypes produced by syn4morphants at 18 somites stage, with or without syn4 mRNA. Lateral views, dorsal to the top and anterior to the left in C-D’’.
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