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Fig. 6
Inhibition of ATM attenuated apoptosis induced by MBZ in the zebrafish retina. Zebrafish were exposed to 0.5 μM MBZ or 0.1% DMSO with or without 2 μM KU-55933 from 2 to 3 dpf. After exposure, zebrafish were subjected to TUNEL staining. The areas of apoptotic signal in the retina were measured and normalized by the area of retina. n = 8 per each group except for 0.1% DMSO and 2 μM KU-5593 (n = 5). *p < 0.05 compared with control. Scale bar: 50 μm.
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