Fig. 6
(a) 3-D LSFM revealed the distinct helical organization of individual cardiomyocyte fibers from the right ventricular wall to septum to left ventricular walls (zones 1, 2, and 3), providing insights into the mechanics of ventricular contraction in RV vs. LV. Endocardial structure of the left atrial appendage revealed the muscular ridge and muscular trabeculation (zone 4). The yellow curved arrows indicate the orientation of cardiomyocyte fibers. (b) Ultrastructure in the RV (zone 1) and LV cavity (zone 2) unravel trabeculation/papillary muscle (zone 1). LV: left ventricle; RV: right ventricle; LA: left atrium.