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Fig. 1
Chd acts downstream of the FGF signaling pathway to induce the anterior and posterior neuroectoderm. Each image represents the expression pattern of otx2 or hoxb1b in (A and B) wild-type embryos, (C and D) uninjected ichabod embryos, (E and F) FGF8 mRNA-injected ichabod embryos, and (G and H) FGF8 mRNA and MOdkk1b-injected ichabod embryos. All embryos are shown at 80% epiboly stage in lateral views. Scale bars represent 100 µm.
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Reprinted from Developmental Biology, 424(2), Tanaka, S., Hosokawa, H., Weinberg, E.S., Maegawa, S., Chordin and dickkopf-1b are essential for the formation of head structures through activation of the FGF signaling pathway in zebrafish, 189-197, Copyright (2017) with permission from Elsevier. Full text @ Dev. Biol.