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Fig. 4
Overexpression of myr-Akt increases brain size in zebrafish embryos. (A) Morphology of zebrafish embryos injected with either control mRNA (left panels) or myr-Akt mRNA (right panels). Scale bar = 250 μm for top panels, and 100 µm for bottom panels. (B) Relative brain size measurements based on horizontal brain height (H) or vertical brain length (V), divided by inner ear to tail embryo length (L). Injection of myr-Akt significantly increased brain size compared to controls. N = 20 total embryos measured from two independent microinjection experiments, 10 embryos per group (*P < 0.0001).
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Full text @ Front Endocrinol (Lausanne)