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Fig. 5
Microglia proliferation upon the induction of neuronal cell death. (A) Immunofluorescence staining in the olfactory bulbs of 3-month-old treated MTZ-treated and DMSO-treated (control) fish. (B) Intravital imaging in 7 dpf zebrafish larvae with Apoe-driven GFP undergoing NTR-mediated neuronal cell death, showing the presence of dividing zebrafish microglia upon neuronal death. n = 3. Scale bar = 40 µm in (A). For quantification in (A) cells were counted in 3 selected volumes in the olfactory bulb (4.0 × 10 − 4 mm3) per fish (n = 3). Error bars represent standard deviation, *P < 0.05 (Student's t-test).
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