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Fig. 4
pappaap170 Mutants Show Reduced Swim Bladder Inflation, Habituation, and Survival
(A) pappaap170 mutants appear grossly normal at 5 dpf, with exception of some showing an uninflated swim bladder.
(B) pappaap170 larvae show startle habituation deficit at 5 and 12 dpf.
(C) Kaplan-Meier survival curve shows reduced viability in pappaap170 mutants. *p < 0.001, one-way ANOVA (with Bonferonni correction) versus pappaa+/+, **p < 0.0001 Mantel-Cox test versus wild-type siblings. N = number of larvae shown within bars (B) or in legend (C). Error bars indicate SEM.
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