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Fig. 9
Mutations in HCFC1 differentially affect craniofacial development. (A-F) Staining of cartilage with Alcian blue on non-injected (NI), hcfc1b MO, or hcfc1b MO co-injected with the indicated mutated version of HCFC1. Numbers of animals affected are presented in Supplementary Table 5. Embryos were stained at 5 days post fertilization and manual dissection of the viscerocranium and neurocranium was performed. Neurocranium is depicted in A-F and the viscerocranium is depicted in A′-F′.
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Reprinted from Developmental Biology, 396(1), Quintana, A.M., Geiger, E.A., Achilly, N., Rosenblatt, D.S., Maclean, K.N., Stabler, S.P., Artinger, K.B., Appel, B., Shaikh, T.H., Hcfc1b, a zebrafish ortholog of HCFC1, regulates craniofacial development by modulating MMACHC expression, 94-106, Copyright (2014) with permission from Elsevier. Full text @ Dev. Biol.