ZFIN Image: Schindler et al., 2014, Fig. S7

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Figure Caption

Fig. S7

Endocardium is present in embryos overexpressing hand2. (A-H) Lateral views of live embryos at 30 hpf depict (A-B) embryonic morphology and (C-H) expression of the transgene Tg(kdrl:GRCFP) in the vasculature of (A,C,E,F) nontransgenic embryos and (B,D,G,H) Tg(hsp70:hand2) embryos, following heat shock at 10 hpf. (C-D) General vascular patterning and sprouting of intersomitic vessels (inset) is intact in embryos overexpressing hand2 (D). (E-H) Partial reconstructions of confocal z-stacks (E,G) and representative single slices (F,H) highlight the endocardium (arrows): just as in nontransgenic embryos (E,F), a thin layer of endocardial tissue lines the entire heart tube in embryos overexpressing hand2 (G,H).

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