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Fig. S6
Role of TGFβ and Shh pathways during cancer progression. Panels A and C represent the Tg(ptf1a;eGFP) controls while panels B and D represent eGFPKRASG12D positive tumor masses. High levels of TGFβ:mCherry expression in the stroma around pancreatic tumor mass at 4 mpf are depicted in panel (B). Shh:mCherry is highly expressed in cerebellum at 14 dpf (D). All figures are single confocal Z-stack planes. Normal tissues and tumor masses are in green, while activity of Shh and TGFβ are in red. Scale bar is 50 μm.
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Full text @ Dis. Model. Mech.