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Fig. S2
Increased hepatocyte proliferation induced by 17β-estradiol (B), TCDD (C) and NDMA (D). Zebrafish larvae were treated 50 µg/L 17β-estradiol. 1000 ng/L TCDD or 100 μg/L NDMA from 3 dpf to 5 dpf and liver cryo-sections were prepared and stained by DAPI and PCNA. Increased numbers of proliferating hepatocytes were noted from 17β-estradiol. TCDD and NDMA treatment groups compared to the 0.01% DMSO vehicle control group.
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