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Fig. 3
Sulf1 is specifically upregulated in shh-expressing MFP and LFP cells at the two critical time points of neuronal and OPC generation. Transverse sections through trunk spinal cord are shown; dorsal to the top in all panels. (A-H) Temporal expression of sulf1 (A-D) and shh (E-H). At 12 hpf, MFP (arrows) expresses shh (E) but not sulf1 (A). From 14 hpf, both transcripts are detected in MFP cells (arrows, B,F). At 36 hpf, sulf1 (D) and shh (H) are expressed in MFP and LFP (brackets). Dashed lines outline the ventral border of the neural tube. Scale bars: 20 μm.
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