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Fig. S7

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ZDB-IMAGE-140612-14
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Figures for Nesin et al., 2014
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Fig. S7 Overexpression of STIM1_R304W causes hypoplastic caudal vein formation in developing zebrafish embryos. (A–D) Lateral views of a control (A) or STIM1_R304W (C)-injected Tg(Fli1:GFP) transgenic embryo expressing GFP in endothelial cells and hence allowing the visualization of developing blood vessels 48 hpf. B and D are magnified views of the boxed area in A in the respective embryos, showing that the caudal vein in the STIM1_R304W injected embryos (C) appears hypoplastic compared with the controls (B). (E) Percent distribution of normal vs. abnormal embryos as determined by phenotypic aberrations of the caudal vein (**P < 0.001, ***P < 0.0001).

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