IMAGE

Fig. S9

ID
ZDB-IMAGE-140506-58
Genes
Antibodies
Source
Figures for Pavlou et al., 2014
Image
Figure Caption

Fig. S9

Simultaneous knockdown of sox2 and BMP rescues the number of PhRs. (A) DMSO-treated control embryos at 28 hpf, with PhR in green (Tg(aanat2:GFP)) and Sox2 in red. (B) Dorsomorphin treatment, that inhibits the BMP pathway, leads to a reduced number of PhRs, while Sox2 expression is normal. (C) Knockdown of sox2 leads to increased number of PhRs. (D) Simultaneous inhibition of sox2 and BMP results in a number of PhR similar to the DMSO-treated control siblings. (E) Average number of PhR in DMSO-treated (purple bar), dorsomorphin-treated (green bar), sox2 morphant treated with DMSO (orange bar) and sox2 morphant treated with dorsomorphin (red bar) embryos. Confocal maximum projections of 28 hpf embryos, error bars represent ± standard error, * = p-value <0.05 (MWU test), ** = p-value <0.001 (MWU test).

Figure Data
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One